One of them is the atherogenic factor, what a dietitian, therapist, and endocrinologist can say. In addition, whether aip is associated with the risk of acute coronary syndrome acs in very young adults has not been well established. Pdf lipid profile and atherogenic index of plasma aip in. Atherogenic index in recent years has started to gain importance as an indicator of atherosclerosis. Its level has an important role in assessing the degree of activity of the atherosclerotic process and related diseases. Atherogenic definition of atherogenic by the free dictionary. What is the abbreviation for atherogenic index of plasma. Understanding the relationship between atherogenic index of plasma and cardiovascular disease risk factors among staff of an university in malaysia. Lipid profile and atherogenic index have been shown to be significant predictors for metabolic abnormalities including dyslipidemia, atherosclerosis, hypertension and cardiovascular disease. Pdf lipid profile and atherogenic index of plasma aip. What is an atherogenic diet an atherogenic diet is one that promotes atheromas, which are inflamed plaques on the insides of arteries. The high prevalence, severity, and prematurity of coronary artery disease cad in the indian population cannot be. Definition, atherogenic diet and measurement of the atherogenic index by dr.
Atherogenic dyslipidemia is the main risk factor of acute coronary syndrome. Atherogenic index of plasma aip in individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a clustering of risk factors such as abdominal obesity, impaired fasting glucose, increased blood pressure, low hdlcholesterol hdlc, increased triglycerides tgs, and an increase in. It is well established that elevation of serum ldl is a major cause of atherosclerosis and coronary heart disease chd. Sep 15, 2017 medicine that initiates or accelerates atherogenesis. The atherogenic index of plasma is a strong and independent predictor for coronary artery disease in the chinese han population. Comparative study for atherogenic index of plasmaaip. Cardiovascular cv diseases are a serious concern in rheumatoid arthritis ra, accounting for approximately onethird to onehalf of all rarelated deaths. Pdf advanced atherogenic index for the assessment of. Atherogenic index as a predictor of atherosclerosis in. Atherogenic index of plasma aip calculated as logarithm. Atherogenic index of plasma which is a marker of plasma atherogenicity may be used to asses risk of developing atherosclerosis in postmenopausal women. The use of atherogenic index of plasma in assessing the. Pdf the atherogenic index of plasma is a strong and independent.
Atherogenic lipoprotein phenotype and dietgene interactions. Nov 30, 2016 relations between atherogenic index of plasmaglucose metabolism the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. The most basic task of dealing with the epidemic of cvd is primary prevention of risk factors. Fatty acids profile, atherogenic ia and thrombogenic it. The paucity of data regarding the relationship between atherogenic index of plasma aip and risk of cardiovascular disease cvd in postmenopausal women living in subsaharan africa prompted us to conduct this study which aimed at assessing the interplay between aip and risk of cvd among cameroonian postmenopausal women. Despite a general relation between fat intake and cardiovascular risk factors, the association is often not observed in studies conducted in heterogenic populations, as for population groups, it may differ. Cardiovascular cv diseases are a serious concern in chronic inflammatory diseases. Atherogenic definition of atherogenic by merriamwebster.
Pdf dyslipidemia is one of the most important factors for coronary artery disease cad. Aipatherogenic index of plasma as a significant predictor of cardiovascular risk. Atherosclerosis, a progressive process responsible for most heart disease, is a type of arteriosclerosis or hardening of the arteries. Thanks to the great work, dozens conducted multicentre studies and statistical data processing from a position of evidencebased medicine has become possible to reliably predict the risk of various cardiovascular disease using atherogenic coefficient. Atherogenicity definition of atherogenicity by the free. The atherogenic index of plasma aip, a new comprehensive. Usefullnes of atherogenic indices and caldl level to predict. This was a crosssectional study conducted among 108 postmenopausal. Pdf on nov 1, 2012, sushith and others published lipid profile and atherogenic index of plasma aip in diabetic nonsmokers and smokers in costal karnataka find, read and cite all the research. Nov 14, 2019 pathology the formation of atheromas, especially on the walls of the arteries.
Further largescale studies with balanced sex ratio and vessel lesion numbers should verify the present findings. The atherogenic index of plasma is becoming an increasingly useful formula for predicting your cardiovascular disease risk. As atherogenic index of plasma aip is a strong marker to predict the risk of atherosclerosis and coronary heart disease, we assessed the correlation between aip and other important factors. Many people know such a thing as bad cholesterol, but not everyone knows that behind this extensive definition are more specific indicators. There are also documents showing that there is a strong relationship between total. Atherogenic article about atherogenic by the free dictionary. Cerebral atherosclerosis may result in the impairment of mental activity or, if pronounced, in paralysis of one kind or another. We seek to quantify the analytical precision of the aip using the coefficients of variation cvs of the tg and hdlc assays. It is characterized by high ratio of ldlc to hdlc 8. Knowing your atherogenic index can help you understand how healthy or at risk of atherosclerosis arteriosclerosis you are. Implications in assessment of cardiovascular disease risk. Atherosclerosis is a disease in which the inside of an artery narrows due to the buildup of plaque. Atherogenic index has been suggested to be less susceptible to disease activity variation during large periods of time. Small ldl particles, total ldl particles, and cvd risk besides the traditional blood lipid measurements of ldlc, hdlc, and triglycerides, there now exist a number of alternative measures that assess lipoprotein.
It has been shown that atherogenic index of plasma a ip is a strong marker to predict the risk of atherosclerosis and coronary heart disease12,1722. This is an open access article distributed under the terms of the creative commons attribution. Aip reflect the true relationship between protective and atherogenic lipoprotein and is associated with the size of preand anti atherogenic lipoprotein particle23. Pdf atherogenic index of plasma in postmenopausal women. Ghdl cardiac risk ratio crr cholesterolhdl atherogenic coefficient ac cholesterolhdl results and discussion a total of 148 patients with type 2 dm, 72 male and 76 female were studied to assessed the alteration in lipid profile and atherogenic indices. A triglyceride based index ai can significantly add value when assessing the cardiovascular risk in obese women. Statistical analysis was done using students t test and correlation was. Bhagavath, prashantha 2012 lipid profile and atherogenic index of plasmaaip in diabetic non smokers and smokers in coastal karnataka. The atherogenic index of plasma aip, defined as the base 10 logarithm of the ratio of plasma triglyceride tg to high density lipoprotein cholesterol hdlc, has been employed as a predictor of cardiovascular risk. Relations between atherogenic index of plasmaglucose. Atkins diet program rapidly decreases atherogenic index of.
Obesity, body mass index, lipid profile, atherogenic index introduction historical references to what we now know as the obesity arise early in medical history. Atherogenic index and highdensity lipoprotein cholesterol as. Aip atherogenic index of plasma as a significant predictor of cardiovascular risk. A probable decrease in the atherogenic index was detected in young. Besides the attempts to identify new risk factors, the proper management of traditional cv risk factors such as dyslipidemia should become a priority in the periodic evaluation of every ra patient. The aim of the study was to analyze the associations between dietary fat intake and lipoprotein cholesterol fractions, as well as atherogenic blood properties, in young and middleaged. Lipid profile and atherogenic index of plasmaaip in. Apr, 2019 the value of atherogenic index of plasma aip as a predictive biomarker for coronary artery disease cad remains controversial. In individuals with a genetically influenced atherogenic lipoprotein phenotype, characterized by a predominance of small dense ldl ldl subclass pattern b, lowering of plasma ldl cholesterol levels by diets with. Understanding the relationship between atherogenic index. Genderspecific associations between atherogenic index of. Atherosclerosis of blood vessels in the legs may cause intermittent claudication, ulcers, gangrene, and so forth.
Further, a significant reduction was also recorded in the levels of total cholesterol, triglycerides. Atherogenic definition, capable of producing atheromatous plaques in arteries. The atherogenic index of plasma aip is a critical index that can be used as a standalone index for cardiac risk estimation 8. Atherogenic index of plasma aip is the new marker of atherogenicity, since the aip is related directly to the atherosclerosis risk. Formation of atheromatous deposits, especially on the innermost layer of arterial walls. Introduction cardiovascular disease c vd is the cause of one third of deaths worldwide and this statue will progress because of increasing cvds risk factors 1. Atherogenic index as a predictor of cardiovascular risk. Atherogenic index as a predictor of cardiovascular risk among. Atheromas are the hallmark of a cardiovascular disease called atherosclerosis a primary risk factor for heart attack and stroke. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected. What is the atherogenic index and why it is so important to your health. Atherogenic index of plasma and risk of cardiovascular. Atherogenic lipoprotein profile of plasma is an important risk factor for cvd.
Atherogenic indices such as atherogenic index of plasma aip. This study was to determine the aip and its relationship with other cvd risk factors. Aip abbreviation stands for atherogenic index of plasma. Intake of saturated fatty acids affects atherogenic blood.
Internationa journal of a j institute of medical sciences, 1 2. Pdf aipatherogenic index of plasma as a significant. Atherogenic definition and meaning collins english dictionary. Diet, atherogenic definition of diet, atherogenic by. Atherosclerosis of the renal arteries is usually manifested by persistent hypertension. As atherogenic index of plasma aip is a strong marker to predict the risk of atherosclerosis and coronary heart disease, we assessed the.
Atherogenic definition is relating to or causing atherogenesis. Cameron troup md in hematological diseases atherogenesis is the formation of plaque in the inner lining of the arteries and is associated with coronary heart disease or coronary heart disease. The atherogenic index of plasma which is a mathematical relationship between tg and hdlc has been successfully used as an additional index when assessing cardiovascular cv risk factors 15, 16. Cardiovascular disease cvd is the cause of one third of deaths worldwide and this will progress because of increasing cvds risk factors. Jul 25, 2015 the most basic task of dealing with the epidemic of cvd is primary prevention of risk factors. Atherogenic index of plasma aip was found to be one of the strongest markers in predicting the cardiovascular disease cvd risk. Listing a study does not mean it has been evaluated by the u. Atherogenic index of plasma aip is a novel indicator involved in dyslipidemia. The atherogenic index of plasma is a strong and independent. Research article alloxan induced diabetes mellitus in. This study seeks to use atherogenic indices to evaluate the potential cvd risk among abo blood.
Dyslipidemia is one of the most important factors for coronary artery disease cad. Understanding the relationship between atherogenic index of. Hdlc from tc, all divided by hdlc value and atherogenic index of plasma aip, calculated as logtghdlc is an indicator of plasma atherogenicity which is a significant independent predictor of cvd events john and brunzell, 2008. This study determined the effect of the initial phase of atkins diet program, consisting in 20. This crosssectional study was done among 349 staff of a public university in sarawak. However, the relation between aip and cad in postmenopausal women remains unclear. The concept of precision extended to the atherogenic index of. Lipid profile alteration and atherogenic indices in patients.
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